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In the embryo, the early skeletal muscle originates from the _______. In the adult, skeletal muscle is repaired by fusion of _______ with muscle fibers. Fill in the blanks.

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The prenatal muscle originates from the myotome. The myotome produces presumed myoblasts that form the satellite cells. Answer: myotome / satellite cells.

How is the skeletal muscle originated and repaired?

Myogenesis is the process of skeletal muscle formation during the embryonal stage. Structures derived from the mesodermal produce the firsts muscle fibers of the body, and then other additional fibers.

The myotome is a primitive muscular structure that contains progenitor muscle cells. Embryonary myotome cells produce two types of cells,

  • presumed myoblasts that constitute a store of cells that can multiplicate through mitosis

  • properly said myoblasts that can not suffer mitosis

Some of the presumed myoblasts can differentiate into other cells, and some others remain undifferentiated, turning into satellite cells.

This is, progenitor cells in the myotome originate presumed myoblasts, and then these last ones produce satellite cells located in the postnatal skeletal muscle.

Satellite cells are involved in the postnatal process of muscle repair. They suffer successive mitosis producing new myoblasts and more satellite cells.

  • In the embryo, the early skeletal muscle originates from the  myotome.
  • In the adult, skeletal muscle is repaired by fusion of _Satellite cells_ with muscle fibers.

You can elarn more about the muscle formation and repair at

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