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Water must be removed between the glucose molecule in order to fit together.

Substance present between molecules

The water molecules that are present with glucose molecules must be removed from the glucose model molecules in order to have them easily fit together because the water molecules are present between two glucose molecules so they can't touch each other directly.

If the glucose molecule have water molecules on both of their sides then it is impossible for them to easily fit together in the model so we can conclude that water must be removed between the glucose molecule in order to fit together.

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