Consider the following metabolic reaction:
3-Phosphoglycerate → 2-Phosphoglycerate ΔG°’ = +4.40 kJ/mol

What is the ΔG for this reaction when the concentration of 2-phosphoglycerate is 0.290 mM and the concentration of 3-phosphoglycerate is 2.90 mM at 37°C?

Respuesta :

Answer:

ΔG = -1.53 kJ/mol

Explanation:

The given reaction is:

3-Phosphoglycerate → 2-Phosphoglycerate

The standard Gibbs free energy, ΔG°=+4.40 kJ

[2-Phosphoglycerate] = 0.290 mM

[3-Phosphoglycerate] = 2.90 mM

Temperature T = 37 C = 310 K

The standard Gibbs free energy, ΔG° is related to the free energy change ΔG at a given temperature by the following equation:

[tex]\Delta G =\Delta G^{0}+RTlnQ[/tex]

In this reaction:

[tex]\Delta G =\Delta G^{0}+RTln\frac{[2-Phosphoglycerate]}{[3-Phosphoglycerate]}[/tex]

[tex]\Delta G = 4.40kJ/mol +0.008314 kJ/mol-K*310Kln\frac{[0.290]}{[2.90]}=-1.53 kJ/mol[/tex]